Self-treating with TSO

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The porcine (pig) whipwormA helminth with a tapering whiplike body that lives in the colon. In helminthic therapy, the microscopic eggs of either the human Trichuris trichiura (TTO) or pig Trichuris suis (TSO) are taken in a drink., Trichuris suisThe porcine (pig) whipworm used in helminthic therapy and taken as microscopic eggs (TSO) in a drink every two weeks., is taken in a liquid in the form of minute, barely visible eggs that are referred to as ova, hence the abbreviation, "TSOthe ova (eggs) of the porcine (pig) whipworm, Trichuris suis". Since this species is not adapted to living in humans, it dies approximately 14 days after ingestion, after which it is completely digested, leaving no eggs or worms to be passed in faeces. During its short time in the body, the immature worm hatches from its egg and begins to grow, shedding molecules that modulate the host’s immune system and provide a legitimate target for it to attack. This prevents the immune system from responding inappropriately to innocent targets such as foods and pollens and the host’s own tissues, as happens in autoimmune diseases such as lupus, ulcerative colitisUlcerative colitis (Colitis ulcerosa, UC) is a form of inflammatory bowel disease (IBD) which specifically affects the large intestine, or colon, causing characteristic ulcers, or open sores. The main symptom of active disease is constant diarrhea mixed with blood, of gradual onset. and Crohn’s disease.

Dosing with TSOthe ova (eggs) of the porcine (pig) whipworm, Trichuris suis

Available dose sizes

  • 500 ova
  • 1,000 ova
  • 2,500 ova

Recommended dosing regimen

  • For children under 3 years old, a physician should be involved in decisions about dosing.
  • In very young children (3 years and over), TSOthe ova (eggs) of the porcine (pig) whipworm, Trichuris suis should be introduced using very small doses. These can then be increased gradually and slowly, e.g. initial treatment with 1/5th of the TSO500 dosage, then 2/5, 3/5 and 4/5, followed by 6 doses of TSO500. [1]
  • In young people (8 years and over) with moderate symptoms - one dose of TSO500 every 14 days.
  • In adults with moderate symptoms - one dose of TSO1000 every 14 days.
  • In the elderly and those with long-term illness - one dose of TSO2500 every 14 days.

Those who start with with TSO500 or TSO1000 and do not see a significant improvement in their condition by the 5th dose, should switch to the next higher dose.

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I have seen several autistic patients showing nothing on lower doses, but as soon as they reached TSO2500 the response was great. [2]

The basic dosing regimen consists of a total of 10 doses, one dose being taken every 14 days. In cases of more severe or chronic disease, administration of up to 20 doses may be necessary.

Some people have found that they begin to experience a return of disease symptoms slightly before the next dose is due. In these cases, shortening the period between doses by one or two days will prevent the reappearance of symptoms.

Possible side effects and how to avoid them

Side effects are usually limited to the period immediately following the first dose and typically consist of temporary, mild gastrointestinal symptoms, especially diarrhoea, but the introduction of TSOthe ova (eggs) of the porcine (pig) whipworm, Trichuris suis can also flare existing diseases and even trigger a temporary recapitulation of old injuries and illnesses.

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I'm in the middle of week 3; I did 1000 for the second dose since 500 went fairly well. I have noticed old things flaring up...a wrist injury for dropping a barbell 8 years ago; my interstitial cystitis - which has been quiet for 4 years - flared back up with a vengeance at the end of week 1 and is now settling down; a knee issue I had on and off that was probably part of my overall autoimmune landscape was bothersome for a few days. My colitis is a little flare-y, too, a little blood, gas, and mucus. That, too, is settling a little as of today. Nothing really alarming, although the cystitis was unpleasant. [3]

Occasionally, side effects may continue for several doses but they will eventually reduce in severity.

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I just took my 4th dose (of 2500 TSOthe ova (eggs) of the porcine (pig) whipworm, Trichuris suis to treat ulcerative colitisUlcerative colitis (Colitis ulcerosa, UC) is a form of inflammatory bowel disease (IBD) which specifically affects the large intestine, or colon, causing characteristic ulcers, or open sores. The main symptom of active disease is constant diarrhea mixed with blood, of gradual onset.)… I’ve had some gas issues for the first couple days after the doses. [4] [5]
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I take them every two weeks. I do get diarrhea the day after dosing. It clears in less than 24 hours. [6]
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I have Crohn's. I don't get nausea but I will get diarrhea after every HDCHymenolepis diminuta cysticercoids (Hi-men-o-lep'is dim-a-nu-ta sis-ti-sur-koid) - the larval cysts of the rat tapeworm, Hymenolepis diminuta or TSOthe ova (eggs) of the porcine (pig) whipworm, Trichuris suis dose. It usually is the 2nd day after swallowing them. Rarely lasts into the 3rd but If I am traveling, I don't risk it. [7]

Adaptation regimen

If someone who starts with larger doses finds that these cause diarrhoea or other side effects, they should switch to this adaptation regimen.

  • Two doses of TSO500, followed by
  • two doses of TSO1000, and then
  • six doses of TSO2500.

Dividing doses

If smaller doses are not immediately available, these can be created by dividing the contents of a bottle containing a larger dose. For example, to create doses of 500 from a bottle of 1000 TSOthe ova (eggs) of the porcine (pig) whipworm, Trichuris suis, first shake the bottle to evenly distribute the organisms it contains, then carefully pour out half of its contents to produce a dose of 500. If dividing a bottle of 2500 ova into five doses of 500, it's best not to attempt to pour out a fifth of the liquid by sight. Instead, after shaking the bottle, use a medicine syringe to draw up 3ml of the liquid for each dose. Any ova remaining in the original bottle should be stored in the fridge until required.

Response to TSOthe ova (eggs) of the porcine (pig) whipworm, Trichuris suis

The conditions that appear to respond best to TSOthe ova (eggs) of the porcine (pig) whipworm, Trichuris suis are Crohn’s disease, ulcerative colitisUlcerative colitis (Colitis ulcerosa, UC) is a form of inflammatory bowel disease (IBD) which specifically affects the large intestine, or colon, causing characteristic ulcers, or open sores. The main symptom of active disease is constant diarrhea mixed with blood, of gradual onset., autism and lupus. [8]

Due to the considerable variation in how individuals respond to TSOthe ova (eggs) of the porcine (pig) whipworm, Trichuris suis, it is not possible to predict an accurate timeline that applies to all patients. However, it appears that around 80 percent of patients eventually respond positively to the treatment, although response and remission may take longer in the case of more severe or chronic conditions, or when individuals have been using a different helminthAn intestinal worm which grows large enough to be seen with the naked eye when mature but which is microscopic when administered in helminthic therapy. [https://en.wikipedia.org/wiki/Helminths Wikipedia:Helminths], such as NAthe human hookworm, Necator americanus, [9] before commencing treatment with TSOthe ova (eggs) of the porcine (pig) whipworm, Trichuris suis.

Most people notice the first improvements between dose 4 (after 8 weeks) and dose 6 (after 12 weeks) and typically achieve remission after dose 10 (20 weeks after commencing the treatment). However, response times do vary, and more than 10 doses may be required in the case of patients with very severe or chronic disease. [10]

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I saw improvement after the 4 doses, about 8 weeks. [11]
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It took me until about the 7th dose (14 weeks) to feel better. [12]

Experience gained from the use of TSOthe ova (eggs) of the porcine (pig) whipworm, Trichuris suis in thousands of patients over more than a decade, both in and outside clinical studies, suggests that the earlier in the disease process that treatment is initiated, the more rapidly it will work and the longer remission is likely to last once it is achieved.

If patients stop treatment after remission is achieved, they don’t usually relapse again for between 1 and 3 years and, if they do flare again, resuming dosing with TSOthe ova (eggs) of the porcine (pig) whipworm, Trichuris suis will usually result in a return to remission. It is recommended that those who do flare again should take a periodic maintenance dose, for example 1 dose of TSO500 every 6 or 8 weeks.

One of the benefits of using a short-lived non-human helminth such as TSOthe ova (eggs) of the porcine (pig) whipworm, Trichuris suis or HDCHymenolepis diminuta cysticercoids (Hi-men-o-lep'is dim-a-nu-ta sis-ti-sur-koid) - the larval cysts of the rat tapeworm, Hymenolepis diminuta is that, in comparison with the human-adapted helminthsAn intestinal worm which grows large enough to be seen with the naked eye when mature but which is microscopic when administered in helminthic therapy. [https://en.wikipedia.org/wiki/Helminths Wikipedia:Helminths], NAthe human hookworm, Necator americanus and TTOthe ova (eggs) of the human whipworm, Trichuris trichiura, it is easier to experiment with the size and frequency of doses to find the optimal regimen for each individual.

Storage and survival of TSOthe ova (eggs) of the porcine (pig) whipworm, Trichuris suis

TSOthe ova (eggs) of the porcine (pig) whipworm, Trichuris suis is an very robust organism that can remain viable in soil for up to 9 years while exposed to all types of weather condition, from extremely cold to very hot. [13]

If stored in a refrigerator, TSOthe ova (eggs) of the porcine (pig) whipworm, Trichuris suis can remain viable for a couple of years, making it possible to take advantage of the cheaper multiple packs, and to keep doses in reserve - something which is not possible with HDCHymenolepis diminuta cysticercoids (Hi-men-o-lep'is dim-a-nu-ta sis-ti-sur-koid) - the larval cysts of the rat tapeworm, Hymenolepis diminuta, which will only remain viable for a couple of weeks in a refrigerator. The excellent longevity of stored TSOthe ova (eggs) of the porcine (pig) whipworm, Trichuris suis, and the fact that it usually produces results more rapidly than TTOthe ova (eggs) of the human whipworm, Trichuris trichiura, also make it ideal to be kept in reserve by users of the human hookwormA helminth that lives in the small intestine. Necator americanus (NA) is the only hookworm species used in helminthic therapy. Its microscopic larvae are applied periodically to the skin., NAthe human hookworm, Necator americanus, as an insurance against the loss of their colony, or an interruption in benefits following the use of antibiotics or certain foods.

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I keep TSOthe ova (eggs) of the porcine (pig) whipworm, Trichuris suis for emergencies, such as, if I have to take antibiotics, or I accidentally ingest something that harms my (human) helminthsAn intestinal worm which grows large enough to be seen with the naked eye when mature but which is microscopic when administered in helminthic therapy. [https://en.wikipedia.org/wiki/Helminths Wikipedia:Helminths]. [14]

Where do TSthe porcine (pig) whipworm, Trichuris suis live?

In humans, TSthe porcine (pig) whipworm, Trichuris suis have been observed to settle predominantly in the caecum and the ascending and transverse sections of the colon, [15] as shown by the red text in the following representation.


mouth ➤ oesophagus ➤ stomach ➤ duodenumjejunumileumcaecumAscending colonTransverse colonDescending colon ➤ rectum

The question of possible TSthe porcine (pig) whipworm, Trichuris suis persistence

There is very little evidence to suggest that TSOthe ova (eggs) of the porcine (pig) whipworm, Trichuris suis might develop to adulthood and persist in humans, and some of the evidence that has appeared lacks credibility.

The first two reports, above, both concerned single individuals. In the first, patent infection was claimed on the basis of a biopsy and, in the second, by colonoscopy and the passage of unembryonated whipwormA helminth with a tapering whiplike body that lives in the colon. In helminthic therapy, the microscopic eggs of either the human Trichuris trichiura (TTO) or pig Trichuris suis (TSO) are taken in a drink. eggs in the subject’s faeces.

The subject in the second study had previously hosted the human whipwormA helminth with a tapering whiplike body that lives in the colon. In helminthic therapy, the microscopic eggs of either the human Trichuris trichiura (TTO) or pig Trichuris suis (TSO) are taken in a drink., Trichuris trichiuraThe human whipworm used in helminthic therapy and taken periodically as microscopic eggs (TTO) in a drink. (TTthe human whipworm, Trichuris trichiura), which was assumed by those conducting the study to have been eradicated following the administration of mebendazole. However, the use of mebendazole to eradicate TTthe human whipworm, Trichuris trichiura is not reliable (see Terminating a human whipworm infection) so, in spite of the bold claim by the researchers that they were the first to report a patent TSthe porcine (pig) whipworm, Trichuris suis infection in a human volunteer undergoing TSOthe ova (eggs) of the porcine (pig) whipworm, Trichuris suis treatment, it is likely that the adult whipwormsA helminth with a tapering whiplike body that lives in the colon. In helminthic therapy, the microscopic eggs of either the human Trichuris trichiura (TTO) or pig Trichuris suis (TSO) are taken in a drink. observed in this case were TTthe human whipworm, Trichuris trichiura and not TSthe porcine (pig) whipworm, Trichuris suis. And, as for the unembryonated eggs observed in this subject’s faeces, these may have been from a dose of TSOthe ova (eggs) of the porcine (pig) whipworm, Trichuris suis, which would inevitably contain at least 3% unembryonated eggs since the TSOthe ova (eggs) of the porcine (pig) whipworm, Trichuris suis production method has a maximum embryonation rate of 97%. [16] Also see the additional comments about this case study in this discussion thread.

In the third study, above, only a single sample of Trichuris eggs showed a similarity to sequences of TSthe porcine (pig) whipworm, Trichuris suis.

Overall, the number of reports of TSthe porcine (pig) whipworm, Trichuris suis persistence in humans is minuscule and no adult stage of TSthe porcine (pig) whipworm, Trichuris suis has been observed in any of the clinical trials that have used this species, even though they have included hundreds of patients. To read these studies, search the following page for "Trichuris suisThe porcine (pig) whipworm used in helminthic therapy and taken as microscopic eggs (TSO) in a drink every two weeks.".

It has been reported anecdotally by one researcher that individual TSthe porcine (pig) whipworm, Trichuris suis can survive for as long as 6 weeks, and one TSOthe ova (eggs) of the porcine (pig) whipworm, Trichuris suis self-treaterSomeone who treats their own disease or condition without medical supervision., who had never used any other whipwormA helminth with a tapering whiplike body that lives in the colon. In helminthic therapy, the microscopic eggs of either the human Trichuris trichiura (TTO) or pig Trichuris suis (TSO) are taken in a drink. species, claims to have seen a few adult worms, the last of which was noticed at approximately 12 weeks after her last (10th) dose. However, in the few cases where such brief persistence has been observed, no adverse effects were reported.

Manufacturer and supplier of TSOthe ova (eggs) of the porcine (pig) whipworm, Trichuris suis

The strain of TSOthe ova (eggs) of the porcine (pig) whipworm, Trichuris suis supplied by Tanawisa was originally sourced from the United States Department of Agriculture farms in Baltimore, Maryland, and was used in the studies by Weinstock et al, and in all other clinical trials in humans. [17]

Further reading

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