Helminthic therapy and pregnancy

From Helminthic Therapy wiki
Jump to: navigation, search

Home>Effects of helminthic therapy>Helminthic therapy and pregnancy

Hosting helminthsAn intestinal worm which grows large enough to be seen with the naked eye when mature but which is microscopic when administered in helminthic therapy. [https://en.wikipedia.org/wiki/Helminths Wikipedia:Helminths] during pregnancy is commonplace, with approximately 44 million pregnancies occurring globally each year in women with helminthsAn intestinal worm which grows large enough to be seen with the naked eye when mature but which is microscopic when administered in helminthic therapy. [https://en.wikipedia.org/wiki/Helminths Wikipedia:Helminths]. [1]

De-worming during pregnancy is not advantageous and may be harmful

Many medics have advocated de-worming pregnant women to prevent a range of supposed health risks, but studies have found that, where good antenatal care is provided, de-worming produces no benefits in respect of anaemia, birth weight, perinatal mortality, infant mortality or infant response to immunisation. [2] [3] [4]

Quotein.gif
Deworming did not show consistent benefits for indicators of mortality, anemia, or growth in children younger than five or women of reproductive age. [5]
Quotein.gif
… anthelmintic treatment during pregnancy has no benefit for an infant's response to immunisation, or for their health and development… [6]
Quotein.gif
... treatment may impose more costs than benefits, for example, by increasing the risk of infant eczema. Treatment may also have additional unanticipated effects by altering maternal blood glucose regulation, microbiotaThe specific population of microorganisms living in a certain part of the body, such as the gut. "Microbiome" refers to all the microorganisms living in and on the body, or the genome of these microorganisms. These two terms are often used interchangeably., or hormonal environment. [7]

Both mother and child benefit when helminthsAn intestinal worm which grows large enough to be seen with the naked eye when mature but which is microscopic when administered in helminthic therapy. [https://en.wikipedia.org/wiki/Helminths Wikipedia:Helminths] are hosted during pregnancy

Prenatal exposure to parasiteAn organism that lives in or on another organism (its host) and benefits at the host’s expense. (The organisms used in helminthic therapy are, strictly speaking, not parasites, but mutualists, because they have a mutually beneficial symbiotic relationship with their hosts.) antigens impacts on the strength and width of postnatal immune responsiveness without generating aberrant inflammatory immune responses. Neonates not exposed to parasiteAn organism that lives in or on another organism (its host) and benefits at the host’s expense. (The organisms used in helminthic therapy are, strictly speaking, not parasites, but mutualists, because they have a mutually beneficial symbiotic relationship with their hosts.) antigens have inappropriately increased or decreased gene expression profiles. [8]

Current epidemiological findings suggest that prenatal exposure to helminth infection may have an important effect on the development of the foetal immune response and that this might help prevent the emergence of inflammatory conditions such as allergy. [9]

The presence of helminthsAn intestinal worm which grows large enough to be seen with the naked eye when mature but which is microscopic when administered in helminthic therapy. [https://en.wikipedia.org/wiki/Helminths Wikipedia:Helminths] at delivery has been shown to be inversely related to infantile eczema, supporting the hypothesis that maternal helminth infection protects against this disease. [10]

Studies in mice indicate that helminth infection during pregnancy may reduce the susceptibility of the offspring to allergic airway inflammation. [11] [12]

Helminth infection in the perinatal period protects children from the neurological damage that can accompany bacterial infections, and this protection extends into adulthood. [13]

Antenatal maternal helminth infections are associated with modestly increased IgA responses to oral infant vaccines. [14]

Sepsis, a condition that is hard to recognise and treat, is an increasing cause of complications and death among women in the West, and rates of severe and fatal sepsis during labor and delivery are rising sharply, such that sepsis is now the leading cause of direct maternal death in the UK. [15]

As a helminth infection counterbalances the exacerbated pro-inflammatory immune responses that occur during sepsis, thus improving survival, it is arguable that the presence of a small colony of therapeutic helminthsAn intestinal worm which grows large enough to be seen with the naked eye when mature but which is microscopic when administered in helminthic therapy. [https://en.wikipedia.org/wiki/Helminths Wikipedia:Helminths] might actually prevent a woman developing sepsis. [16]

Hyperemesis gravidarum (HG) is a pregnancy complication characterised by severe nausea, vomiting, weight loss, and possibly dehydration, [17] which is considered more severe than morning sickness. [18] In view of the fact that allergy is the most significant condition associated with HG prior to pregnancy [19] - which suggests a possible allergic or autoimmune component - it is possible that women who are hosting helminthsAn intestinal worm which grows large enough to be seen with the naked eye when mature but which is microscopic when administered in helminthic therapy. [https://en.wikipedia.org/wiki/Helminths Wikipedia:Helminths] might be less likely to develop HG.

Since helminthsAn intestinal worm which grows large enough to be seen with the naked eye when mature but which is microscopic when administered in helminthic therapy. [https://en.wikipedia.org/wiki/Helminths Wikipedia:Helminths] control inflammation, commencing helminthic therapyThe reintroduction to the digestive tract of a controlled number of specially domesticated, mutualistic helminths (intestinal worms) in the form of microscopic eggs or larvae to reconstitute a depleted biome to treat and prevent chronic inflammation, autoimmune disease and other immunological disorders including allergy. prior to pregnancy might help women who have autoimmune disorders such as colitis to stay healthy during pregnancy, [20] and help to spare their offspring adverse, inflammation-related effects on brain development, some of which can result in autism-like features. [21] [22]

Quotein.gif
I am a physician and see absolutely no problem with using HThelminthic therapy while pregnant. In fact, I plan to do it myself later this year. (Posted to a Helminthic Therapy support group.)

Reports by women who hosted a small number of helminthsAn intestinal worm which grows large enough to be seen with the naked eye when mature but which is microscopic when administered in helminthic therapy. [https://en.wikipedia.org/wiki/Helminths Wikipedia:Helminths] while pregnant

One woman who examined all the available evidence on the risks and benefits of hosting helminthsAn intestinal worm which grows large enough to be seen with the naked eye when mature but which is microscopic when administered in helminthic therapy. [https://en.wikipedia.org/wiki/Helminths Wikipedia:Helminths] during pregnancy came to the following conclusion.

Quotein.gif
I got hookwormA helminth that lives in the small intestine. Necator americanus (NA) is the only hookworm species used in helminthic therapy. Its microscopic larvae are applied periodically to the skin. (and just a couple of whipwormsA helminth with a tapering whiplike body that lives in the colon. In helminthic therapy, the microscopic eggs of either the human Trichuris trichiura (TTO) or pig Trichuris suis (TSO) are taken in a drink.) to help keep my immune system in check during my next pregnancy, since my first kid is on the autism spectrum. From my research it seems safe in low doses and can prevent allergy in offspring, another reason I decided to go for this. Not pregnant yet, just planning.

And she reported, at a later date,

Quotein.gif
I hosted whipwormA helminth with a tapering whiplike body that lives in the colon. In helminthic therapy, the microscopic eggs of either the human Trichuris trichiura (TTO) or pig Trichuris suis (TSO) are taken in a drink. and hookwormA helminth that lives in the small intestine. Necator americanus (NA) is the only hookworm species used in helminthic therapy. Its microscopic larvae are applied periodically to the skin. during 2 term pregnancies. The first baby is 2 years old and is free of allergies and autoimmunity, unlike the older sibling who was sick since birth.

Someone else, who had previously had two children with severe eosinophilic esophagitis-related food intolerances, maintained a hookwormA helminth that lives in the small intestine. Necator americanus (NA) is the only hookworm species used in helminthic therapy. Its microscopic larvae are applied periodically to the skin. colony throughout her next pregnancy and delivered a healthy, allergy-free baby. [23]

Another mother has reported,

Quotein.gif
I hosted hookwormA helminth that lives in the small intestine. Necator americanus (NA) is the only hookworm species used in helminthic therapy. Its microscopic larvae are applied periodically to the skin. while pregnant with my second and had no issues. [24]

Mothers, as well as their babies, can benefit by continuing to host helminthsAn intestinal worm which grows large enough to be seen with the naked eye when mature but which is microscopic when administered in helminthic therapy. [https://en.wikipedia.org/wiki/Helminths Wikipedia:Helminths] during their pregnancy.

Quotein.gif
In June of 2016 I decided to try TSOthe ova (eggs) of the porcine (pig) whipworm, Trichuris suis 2500 every 2 weeks, and for the first time, had some real improvement in my (RA-related) inflammation and pain. I got pregnant in September 2016 and from my own research and from talking to Tanawisa, I felt comfortable continuing with the TSOthe ova (eggs) of the porcine (pig) whipworm, Trichuris suis throughout my pregnancy. Because uncontrolled inflammation in a pregnant mother has been proven so detrimental to the health of the child, I decided to bump up my dose of TSOthe ova (eggs) of the porcine (pig) whipworm, Trichuris suis to 2500 every week. Throughout my pregnancy I have had almost no inflammation or joint pain, except for a couple of small flare ups during some stressful events. [25] (This mother also reported, in a different Facebook group, that her baby is healthy.)

The question of whether to introduce helminthsAn intestinal worm which grows large enough to be seen with the naked eye when mature but which is microscopic when administered in helminthic therapy. [https://en.wikipedia.org/wiki/Helminths Wikipedia:Helminths] during pregnancy

Notwithstanding the benefits to be gained by establishing a helminth colony before becoming pregnant, and the lack of any indication that the organisms currently used in helminthic therapyThe reintroduction to the digestive tract of a controlled number of specially domesticated, mutualistic helminths (intestinal worms) in the form of microscopic eggs or larvae to reconstitute a depleted biome to treat and prevent chronic inflammation, autoimmune disease and other immunological disorders including allergy. can harm a developing foetus, the possible risks of commencing helminthic therapyThe reintroduction to the digestive tract of a controlled number of specially domesticated, mutualistic helminths (intestinal worms) in the form of microscopic eggs or larvae to reconstitute a depleted biome to treat and prevent chronic inflammation, autoimmune disease and other immunological disorders including allergy. for the first time during pregnancy are unknown, and two hookwormA helminth that lives in the small intestine. Necator americanus (NA) is the only hookworm species used in helminthic therapy. Its microscopic larvae are applied periodically to the skin. hosts have commented as follows:

Quotein.gif
If it were me, I would feel comfortable infecting myself with helminthsAn intestinal worm which grows large enough to be seen with the naked eye when mature but which is microscopic when administered in helminthic therapy. [https://en.wikipedia.org/wiki/Helminths Wikipedia:Helminths] for the first time before a pregnancy but not during. [26]
Quotein.gif
I made the decision not to inoculate during either of my pregnancies - the first because I didn't have an existing colony and I was worried about the heightened immune response triggering heightened immune responses in my child as well as my ability to take any medications to manage the side effects; the second because I already had an existing colony and felt well enough that I was happy to wait. [27]

If a woman were to start helminthic therapyThe reintroduction to the digestive tract of a controlled number of specially domesticated, mutualistic helminths (intestinal worms) in the form of microscopic eggs or larvae to reconstitute a depleted biome to treat and prevent chronic inflammation, autoimmune disease and other immunological disorders including allergy. while pregnant, and have a miscarriage, or encounter a problem with the new baby, they, or their healthcare providers, might blame the helminthsAn intestinal worm which grows large enough to be seen with the naked eye when mature but which is microscopic when administered in helminthic therapy. [https://en.wikipedia.org/wiki/Helminths Wikipedia:Helminths], and legal action could be taken against whoever supplied them. Since providers of therapeutic helminthsAn intestinal worm which grows large enough to be seen with the naked eye when mature but which is microscopic when administered in helminthic therapy. [https://en.wikipedia.org/wiki/Helminths Wikipedia:Helminths] must act with this possibility in mind, they would be very unlikely to supply helminthsAn intestinal worm which grows large enough to be seen with the naked eye when mature but which is microscopic when administered in helminthic therapy. [https://en.wikipedia.org/wiki/Helminths Wikipedia:Helminths] to anyone who is already pregnant.

Five of the helminth providers recommend waiting until after pregnancy before starting helminthic therapyThe reintroduction to the digestive tract of a controlled number of specially domesticated, mutualistic helminths (intestinal worms) in the form of microscopic eggs or larvae to reconstitute a depleted biome to treat and prevent chronic inflammation, autoimmune disease and other immunological disorders including allergy..

Quotein.gif
In lack of appropriate clinical studies, this supplement should, however, not be taken during pregnancy. (Tanawisa)
Quotein.gif
If you are pregnant or planning on becoming pregnant soon after starting therapy we will not provide hookwormA helminth that lives in the small intestine. Necator americanus (NA) is the only hookworm species used in helminthic therapy. Its microscopic larvae are applied periodically to the skin. to you. (Autoimmune Therapies)
Quotein.gif
Since, this therapy is so new we do not know the effects on the fetus so we do not treat women who are pregnant. (Worm Therapy)
Quotein.gif
Due to a lack of clinical research we would not recommend the treatment for pregnant women. (Wormswell)
Quotein.gif
Due to the lack of clinical data, anyone who is pregnant would need to wait until after the child is born before beginning the treatment. (Symmbio)

And one provider recommends supervision by a physician.

Quotein.gif
If someone wishes to begin to restore their biome while pregnant, they should do so under a physician’s supervision. (Biome Restoration)

Note: if a woman who fell pregnant while hosting human helminthsAn intestinal worm which grows large enough to be seen with the naked eye when mature but which is microscopic when administered in helminthic therapy. [https://en.wikipedia.org/wiki/Helminths Wikipedia:Helminths] wished to terminate the colony, it had been suggested that it would be best to avoid using mebendazole for this purpose. However, a study in 2016 found no association between exposure to mebendazole at any time during pregnancy and negative birth outcomes. [28]

Discussion threads about helminthsAn intestinal worm which grows large enough to be seen with the naked eye when mature but which is microscopic when administered in helminthic therapy. [https://en.wikipedia.org/wiki/Helminths Wikipedia:Helminths] and pregnancy

1. Pregnancy and hookwormsA helminth that lives in the small intestine. Necator americanus (NA) is the only hookworm species used in helminthic therapy. Its microscopic larvae are applied periodically to the skin.. Sept 2010. [29]

2. Thinking of inoculating while pregnant. Aug/Sept 2011. [30]

3. Experiences of pregnancy as a current or recent helminth host. Sept 2013. [31]

4. A doctor’s concern about a hookwormA helminth that lives in the small intestine. Necator americanus (NA) is the only hookworm species used in helminthic therapy. Its microscopic larvae are applied periodically to the skin.-hosting pregnant patient. Dec 2016. [32]

See also


SimpleHTLogo(18x18).gif Helminthic Therapy Wiki: documenting the science, management, experience and results of helminth replacement therapy.