Helminthic therapy and Parkinson's disease

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Home>Effects of helminthic therapy>Helminthic therapy and Parkinson's disease

There are three major independent lines of evidence suggesting that helminthic therapyThe reintroduction to the digestive tract of a controlled number of specially domesticated, mutualistic helminths (intestinal worms) in the form of microscopic eggs or larvae to reconstitute a depleted biome to treat and prevent chronic inflammation, autoimmune disease and other immunological disorders including allergy. may be effective in the treatment of Parkinson’s disease.

1. The role of the gut-brain connection in Parkinson’s disease is well-known and widely accepted.

2. There is anecdotal evidence suggesting that helminthsAn intestinal worm which grows large enough to be seen with the naked eye when mature but which is microscopic when administered in helminthic therapy. [https://en.wikipedia.org/wiki/Helminths Wikipedia:Helminths] will halt the progression of Parkinson’s and even reverse many of its effects.

While anecdotes are not widely accepted as strong evidence in modern medicine, it would seem reasonable to invoke the “parachute paradigm” on this issue: if, like a pilot who jumps from an aeroplane and deploys a parachute, the patient is rescued from an otherwise certain fate, and if the mechanism makes perfect sense, then the anecdote should surely be taken seriously.

3. The authors of research published in Nature, in June 2017, concluded that Parkinson’s disease is related to autoimmunity.

That there is a relationship between the disease and autoimmunity has been known for several years, but scientists have been slow to embrace the idea.

A study reported in 2018 showed that the use of immunosuppressant drugs may keep Parkinson's disease at bay, and may also slow progression of the disease if it develops.

HelminthsAn intestinal worm which grows large enough to be seen with the naked eye when mature but which is microscopic when administered in helminthic therapy. [https://en.wikipedia.org/wiki/Helminths Wikipedia:Helminths] can achieve similar beneficial effects to immunosuppressants without the longterm adverse side effects, and they are well known to be extremely effective in the treatment of a range of autoimmune conditions. Therefore, it can be concluded that helminthsAn intestinal worm which grows large enough to be seen with the naked eye when mature but which is microscopic when administered in helminthic therapy. [https://en.wikipedia.org/wiki/Helminths Wikipedia:Helminths] may also prevent and treat Parkinson’s disease, as suggested by the experience of one individual.

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They (pig whipwormsA helminth with a tapering whiplike body that lives in the colon. In helminthic therapy, the microscopic eggs of either the human Trichuris trichiura (TTO) or pig Trichuris suis (TSO) are taken in a drink. - TSOthe ova (eggs) of the porcine (pig) whipworm, Trichuris suis) have a brilliant effect on dyskinesia and the need for drugs. It reduces the need for levadopa considerably. Watch the video

NB. After the discovery in, 2017, that a molecule in the anthelminthic drug, niclosamide, might be able to protect against Parkinson’s disease-related neuronal damage, [1] it is possible that patients with this disease may be offered treatment with niclosamide.

Since this drug specifically targets tapewormsA helminth with a flat, ribbon-like, segmented body. Only the murine (rat) tapeworm, Hymenolepis diminuta, is used in helminthic therapy and this generally does not reach adulthood in humans so requires regular dosing of HDC., in which it inhibits glucose uptake, oxidative phosphorylation and anaerobic metabolism, any patient taking niclosamide might not benefit from helminthic therapyThe reintroduction to the digestive tract of a controlled number of specially domesticated, mutualistic helminths (intestinal worms) in the form of microscopic eggs or larvae to reconstitute a depleted biome to treat and prevent chronic inflammation, autoimmune disease and other immunological disorders including allergy. using the rat tapewormA helminth with a flat, ribbon-like, segmented body. Only the murine (rat) tapeworm, Hymenolepis diminuta, is used in helminthic therapy and this generally does not reach adulthood in humans so requires regular dosing of HDC., Hymenolepis diminutaA murine (rat) tapeworm used in helminthic therapy that generally does not mature in humans and is taken as cysticerci (HDC) in a drink every 2 or 3 weeks. (HDCthe cysticercoids (larval cysts) of the rat tapeworm, Hymenolepis diminuta).

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